Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein

Name: Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein
Brand: Novus Biologicals
SKU: NBP3-18196

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18196

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

HEK293

Tag

His (C-Term)

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all Serpin A8/Angiotensinogen Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-terminal 6xHis tag corresponding to the amino acids Asp34-Ala485 of Human Serpin A8/Angiotensinogen.

Source: HEK293

(Accession #: NP_000020.1)

Store at -20C to -80C long term. After reconstitution, the product is stable at -20C for 3 months, and 2-8C for up to 1 week.

Purity

>97%, by SDS-PAGE

Endotoxin Level

< 0.1 EU/ug of the protein by LAL method

Activity

Measured by its binding ability in a functional ELISA. Immobilized Human Serpin A8/Angiotensinogen at 1 ug/ml (100 ul/well) can bind Anti-Serpin A8/Angiotensinogen rabbit Mab with a linear range of 0.78-2.44 ng/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein

Bioactivity: Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein [NBP3-18196] - Immobilized Human Serpin A8/Angiotensinogen at 1 ug/mL (100 uL/well) can bind Anti Serpin A8/Angiotensinogen rabbit Mab with a linear range of 0.78-2.44 ng/mL.

SDS-PAGE: Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein [NBP3-18196]

SDS-Page: Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein [NBP3-18196] - Recombinant Human Serpin A8/Angiotensinogen Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 65-70 kDa.

Formulation, Preparation and Storage

NBP3-18196

Formulation	Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4
Concentration	Lyoph
Reconstitution	Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C.

Background: Serpin A8/Angiotensinogen

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternate Names

AGT, Angiotensin II, Angiotensinogen, Aogen, PAT

Gene Symbol

AGT

Additional Serpin A8/Angiotensinogen Products

Product Documents for Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Human Serpin A8/Angiotensinogen His (C-Term) Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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