SODD/BAG4 Antibody Blocking Peptide

Name: SODD/BAG4 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NBP1-76897PEP

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76897PEP

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all SODD/BAG4 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 15 amino amino terminus of human SODD.

Source: Synthetic

(Accession #: AF111116)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76897. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for SODD/BAG4 Antibody Blocking Peptide

Western Blot: SODD/BAG4 Antibody Blocking Peptide [NBP1-76897PEP]

Western Blot: BAG4 Peptide [NBP1-76897PEP] - Incubating the peptide with equal volume of antibody for 30 min at 37C usually completely blocks the antibody activity in Western blotting.

Formulation, Preparation and Storage

NBP1-76897PEP

Formulation	PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative	0.02% Sodium Azide
Concentration	0.2 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: SODD/BAG4

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Long Name

Silencer of Death Domains

Alternate Names

BAG4

Gene Symbol