SODD/BAG4 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56696PEP

Novus Biologicals, part of Bio-Techne
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NB100-56696PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all SODD/BAG4 Proteins and Enzymes »

Product Specifications

Description

Application Notes

This peptide is useful as a blocking peptide for NB100-56696. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-56696 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB100-56696PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: SODD/BAG4

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Long Name

Silencer of Death Domains

Alternate Names

BAG4

Gene Symbol

BAG4

Additional SODD/BAG4 Products

Product Documents for SODD/BAG4 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SODD/BAG4 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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