Recombinant Human TANK Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-22948

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

SDS-PAGE

View all TANK Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1-119 of Human TANK

Source: E.coli

Amino Acid Sequence: MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

13.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TANK Protein

SDS-PAGE: Recombinant Human TANK Protein [NBC1-22948]

SDS-PAGE: Recombinant Human TANK Protein [NBC1-22948]

SDS-Page: TANK Protein [NBC1-22948] - TANK, 13.6 kDa (119 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Formulation, Preparation and Storage

NBC1-22948
Formulation 20 mM Tris-HCl buffer (pH8.0)
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TANK

TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

TRAF Family Member-Associated NFKB Activator

Alternate Names

I-TRAF

Gene Symbol

TANK

Additional TANK Products

Product Documents for Recombinant Human TANK Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human TANK Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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