Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein

Name: Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein
Brand: Novus Biologicals
SKU: NBP2-61985

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61985

Submit a review

Product Datasheet / COA

100% Guarantee

Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Baculovirus

Tag

hIgG-His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all TGF-beta RI/ALK-5 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal hIgG-His-tag and corresponding to the amino acids 27-126 of Human TGF-beta RI/ALK-5

Source:Baculovirus

Amino Acid Sequence: ADLLLPGATA LQCFCHLCTK DNFTCVTDGL CFVSVTETTD KVIHNSMCIA EIDLIPRDRP FVCAPSSKTG SVTTTYCCNQ DHCNKIELPT TVKSSPGLGP VELVEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Predicted Molecular Mass

38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein

SDS-PAGE: Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein [NBP2-61985]

SDS-Page: Recombinant Human TGF-beta RI/ALK-5 Isoform 1 Protein [NBP2-61985] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP2-61985

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TGF-beta RI/ALK-5

TGF beta Receptor I is encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Long Name

Transforming Growth Factor beta Receptor I

Alternate Names

ALK-5, SKR4, TGF-bRI, TGFbetaRI, TGFBR1

Gene Symbol

TGFBR1

Additional TGF-beta RI/ALK-5 Products

Product Documents for Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein

Product Datasheets

Download Product Datasheets

COA

Product Specific Notices for Recombinant Human TGF-beta RI/ALK-5 Isoform 1 hIgG-His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews