Recombinant Human Tmp21/p23 His Protein

Name: Recombinant Human Tmp21/p23 His Protein
Brand: Novus Biologicals
SKU: NBP2-22885

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22885

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Tmp21/p23 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 32-185 of Human Tmp21/p23

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSISFHLPI NSRKCLREEI HKDLLVTGAY EISDQSGGAG GLRSHLKITD SAGHILYSKE DATKGKFAFT TEDYDMFEVC FESKGTGRIP DQLVILDMKH GVEAKNYEEI AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTR

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Tmp21/p23 His Protein

SDS-PAGE: Recombinant Human Tmp21/p23 His Protein [NBP2-22885]

SDS-Page: TMP21 Protein [NBP2-22885]

Formulation, Preparation and Storage

NBP2-22885

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 30% glycerol
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tmp21/p23

TMED10 is a member of the EMP24/GP25L/p24 family and a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. Recombinant human TMED10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

21 kDa Transmembrane Trafficking Protein

Alternate Names

p24delta, S31I125, S31III125, TMED10

Gene Symbol

TMED10

Additional Tmp21/p23 Products

Product Documents for Recombinant Human Tmp21/p23 His Protein

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COA

Product Specific Notices for Recombinant Human Tmp21/p23 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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