TRIM5 alpha Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76600PEP

Novus Biologicals, part of Bio-Techne
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NBP1-76600PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all TRIM5 alpha Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 15 amino acids from the carboxy terminus of rhesus monkey TRIM5alpha.

Source: Synthetic

(Accession #: ABG67967)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76600. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-76600PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: TRIM5 alpha

TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Alternate Names

EC 6.3.2, EC 6.3.2.-, RING finger protein 88, RNF88tripartite motif protein TRIM, TRIM5alpha, tripartite motif containing 5, tripartite motif protein TRIM5, tripartite motif-containing 5, tripartite motif-containing protein 5

Gene Symbol

TRIM5

Additional TRIM5 alpha Products

Product Documents for TRIM5 alpha Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRIM5 alpha Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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