Recombinant Mouse Uteroglobin/SCGB1A1 Protein

Name: Recombinant Mouse Uteroglobin/SCGB1A1 Protein
Brand: Novus Biologicals
SKU: NBP2-35187

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35187

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all Uteroglobin/SCGB1A1 Proteins and Enzymes »

Product Specifications

Description

A disulfide-linked homodimeric protein containing two 75 amino acid polypeptide chains corresponding to Uteroglobin/SCGB1A1 Source: E. coli

Uniprot ID: Q06318

Amino Acid Sequence: DICPGFLQVL EALLMESESG YVASLKPFNP GSDLQNAGTQ LKRLVDTLPQ ETRINIMKLT EKILTSPLCK QDLRF

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Purity

> 98 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 0.1 EU/ug of Uteroglobin/SCGB1A1 as determined by LAL method.

Predicted Molecular Mass

16.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Uteroglobin/SCGB1A1 protein is fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ug/ml, corresponding to a specific activity of > 200 IU/mg.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse Uteroglobin/SCGB1A1 Protein

SDS-PAGE: Recombinant Mouse Uteroglobin/SCGB1A1 Protein [NBP2-35187]

SDS-Page: Mouse Uteroglobin/SCGB1A1 Protein [NBP2-35187]

Formulation, Preparation and Storage

NBP2-35187

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: Uteroglobin/SCGB1A1

Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is encoded by thek SCGB1A1 gene. Uteroglobin is the founding protein of the secretoglobin family, whose members are small, secreted, disulfide-bridged dimeric proteins found in mammals only. Uteroglobin is specifically expressed in clara cells in the lungs. It is multifunctional and found in various tissues in various names such as: uteroglobin (UG, UGB), uteroglobin-like antigen (UGL), blastokinin, clara cell secretory protein (CCSP), clara cell 16 kD protein (17 in rat/mice), clara Cell-Specific 10 kD protein (CC10), human protein 1, urine protein 1 (UP-1), polychlorinated biphenyl-binding protein (PCB-BP), human clara cell phospholipid-binding protein (hCCPBP), secretoglobin 1A member 1 (SCGB1A1). Its putative functions include immunomodulation, progesterone binding (weak in some animals, especially weak in humans), phospholipase A2 inhibitor etc. Murine uteroglobin shares 54% amino acid sequence identity with human uteroglobin.

Alternate Names

Blastokinin, CC10, CC16, CCPBP, CCSP, Clara, PCB-BP, SCGB1A1, UGB

Gene Symbol

SCGB1A1

Additional Uteroglobin/SCGB1A1 Products

Product Documents for Recombinant Mouse Uteroglobin/SCGB1A1 Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Mouse Uteroglobin/SCGB1A1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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