Recombinant Human Uteroglobin/SCGB1A1 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35126

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Accession #

P11684

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all Uteroglobin/SCGB1A1 Proteins and Enzymes »

Product Specifications

Description

A disulfide-linked homodimeric protein containing two 70 amino acid polypeptide chains corresponding to Uteroglobin/SCGB1A1 Source: E. coli

Uniprot ID: P11684

Amino Acid Sequence: EICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN

Purity

> 98 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 0.1 EU/ug of Uteroglobin/SCGB1A1 as determined by LAL method.

Predicted Molecular Mass

15.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Uteroglobin/SCGB1A1 protein is fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ug/ml, corresponding to a specific activity of > 200 IU/mg

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Uteroglobin/SCGB1A1 Protein

SDS-PAGE: Recombinant Human Uteroglobin/SCGB1A1 Protein [NBP2-35126]

SDS-PAGE: Recombinant Human Uteroglobin/SCGB1A1 Protein [NBP2-35126]

SDS-Page: Human Uteroglobin/SCGB1A1 Protein [NBP2-35126]

Formulation, Preparation and Storage

NBP2-35126
Formulation Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at
Format Carrier-Free
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: Uteroglobin/SCGB1A1

Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is encoded by thek SCGB1A1 gene. It is the founding protein of the secretoglobin family, whose members are small, secreted, disulfide-bridged dimeric proteins found in mammals only. Uteroglobin is specifically expressed in clara cells in the lungs. It is multifunctional and found in various tissues in various names such as: uteroglobin (UG, UGB), uteroglobin-like antigen (UGL), blastokinin, clara cell secretory protein (CCSP), clara cell 16 kD protein (17 in rat/mice), clara Cell-Specific 10 kD protein (CC10), human protein 1, urine protein 1 (UP-1), polychlorinated biphenyl-binding protein (PCB-BP), human clara cell phospholipid-binding protein (hCCPBP), secretoglobin 1A member 1 (SCGB1A1). Its putative functions include immunomodulation, progesterone binding (weak in some animals, especially weak in humans), phospholipase A2 inhibitor etc. Human uteroglobin shares 50 % ~ 60 % amino acid sequence identity with murine, rat, equine and bovine uteroglobins.

Alternate Names

Blastokinin, CC10, CC16, CCPBP, CCSP, Clara, PCB-BP, SCGB1A1, UGB

Gene Symbol

SCGB1A1

UniProt

P11684

Additional Uteroglobin/SCGB1A1 Products

Product Documents for Recombinant Human Uteroglobin/SCGB1A1 Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human Uteroglobin/SCGB1A1 Protein

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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