1R,3R-RSL3

Name: 1R,3R-RSL3
Brand: Tocris Bioscience
SKU: 6687

Tocris Bioscience, part of Bio-Techne | Catalog # 6687

COA / SDS

Negative control for 1S,3R-RSL3 (Cat. No. 6118)

Key Product Details

Description:	Negative control for 1S,3R-RSL3 (Cat. No. 6118)
Chemical Name:	(1R,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Purity:	≥98% (HPLC)
Molecular Weight:	440.88

View Full Technical Details for 1R,3R-RSL3

Technical Data
Citations

Biological Activity for 1R,3R-RSL3

1R,3R-RSL3 is a negative control for 1S,3R-RSL3 (Cat. No. 6118).

Licensing Information

Sold with the permission of Columbia University.

Technical Data for 1R,3R-RSL3

M. Wt	440.88
Formula	C₂₃H₂₁ClN₂O₅
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1219810-15-7
PubChem ID	1750827
InChi Key	TXJZRSRTYPUYRW-WIYYLYMNSA-N
Smiles	COC([C@H]1CC2=C([C@@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=CC=CC=C24)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 1R,3R-RSL3

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	44.09	100

Preparing Stock Solutions for 1R,3R-RSL3

The following data is based on the product molecular weight 440.88.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.27 mL	11.34 mL	22.68 mL
5 mM	0.45 mL	2.27 mL	4.54 mL
10 mM	0.23 mL	1.13 mL	2.27 mL
50 mM	0.05 mL	0.23 mL	0.45 mL

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Reconstitution Calculator

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References for 1R,3R-RSL3

References are publications that support the biological activity of the product.

Yang Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc.Natl.Acad.Sci.U.S.A. 2016 PMID: 27506793