MC3 LNP Luciferase

Name: MC3 LNP Luciferase
Brand: Tocris Bioscience
SKU: 8889

Tocris Bioscience, part of Bio-Techne | Catalog # 8889

COA / SDS

Dlin-MC3 containing LNP for in vitro and in vivo deliver of luciferase mRNA

Key Product Details

Description:

Dlin-MC3 containing LNP for in vitro and in vivo deliver of luciferase mRNA

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Technical Data
Citations

Biological Activity for MC3 LNP Luciferase

MC3 LNP Luciferase is a fully formulated lipid nanoparticle (LNP) composed of DLin-MC3-DMA, DSPC, cholesterol, DMGPEG2000 with the molar ratio 50:10:38.5:1.5.11 providing a convenient, ready to use, benchmark LNP formulation. Contains a reporter luciferase mRNA for in vitro and in vivo bioluminescence detection when used with D-luciferin (Cat. No. 5427).

Do not use a vortex to resuspend LNPs as this can disrupt the lipid membrane and damage particle integrity.

Technical Data for MC3 LNP Luciferase

Storage	Store at -80°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for MC3 LNP Luciferase

Solubility

Soluble in TBS buffer solution (10% sucrose, pH 7.5). Supplied in 200 µL aliquots, 0.05 µg/µL RNA concentration

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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References for MC3 LNP Luciferase

References are publications that support the biological activity of the product.

Brown Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles. Cell 2024 PMID: 39260374

MC3 LNP Luciferase

Tocris Bioscience, part of Bio-Techne | Catalog # 8889

Key Product Details

Biological Activity for MC3 LNP Luciferase

Technical Data for MC3 LNP Luciferase

Solubility for MC3 LNP Luciferase

Dilution Calculator

Reconstitution Calculator

References for MC3 LNP Luciferase

Product Documents for MC3 LNP Luciferase

COA

Certificate of Analysis

SDS

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