NSC 636819

Name: NSC 636819
Brand: Tocris Bioscience
SKU: 5287
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 5287

(1)

Citations (4)

COA / SDS

KDM4A/KDM4B inhibitor

Key Product Details

Chemical Name:	1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene
Purity:	≥98%

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Technical Data
Citations / Reviews (1)

Biological Activity for NSC 636819

NSC 636819 is a KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.

Technical Data for NSC 636819

Formula	C₂₂H₁₂Cl₄N₂O₄
Storage	Store at +4°C
Purity	≥98%
CAS Number	1618672-71-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for NSC 636819

Solubility

Soluble Soluble to 10 mM in DMSO

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References for NSC 636819

References are publications that support the biological activity of the product.

Chu et al. KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J.Med.Chem., 2014;57:5975 PMID: 24971742

NSC 636819

Tocris Bioscience, part of Bio-Techne | Catalog # 5287

Key Product Details

Biological Activity for NSC 636819

Technical Data for NSC 636819

Solubility for NSC 636819

Dilution Calculator

Reconstitution Calculator

References for NSC 636819

Product Documents for NSC 636819

COA

Certificate of Analysis

SDS

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