Histone Demethylase Inhibitors: Small Molecules and Peptides
Histone demethylases (KDMs), a family of enzymes, help catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues, which is catalyzed by histone methyltransferases.
15 results for "Histone Demethylase Inhibitors Small Molecules and Peptides" in Products
15 results for "Histone Demethylase Inhibitors Small Molecules and Peptides" in Products
Histone Demethylase Inhibitors: Small Molecules and Peptides
Histone demethylases (KDMs), a family of enzymes, help catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues, which is catalyzed by histone methyltransferases.
Histone demethylase inhibitor; cell permeable
| Alternate Names: | 5-carboxy-8HQ |
| Chemical Name: | 8-Hydroxy-5-quinolinecarboxylic acid |
| Purity: | ≥99% (HPLC) |
Pan-histone demethylase inhibitor
| Chemical Name: | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Purity: | ≥99% (HPLC) |
Histone KDM inhibitor; cell permeable
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥99% (HPLC) |
Selective inhibitor of lysine demethylase 5
| Chemical Name: | 2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent JMJD3/UTX inhibitor
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
| Purity: | ≥99% (HPLC) |
Selective KDM2/7 inhibitor
| Chemical Name: | N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
| Purity: | ≥98% (HPLC) |
KDM4A/KDM4B inhibitor
| Chemical Name: | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
| Purity: | ≥98% (HPLC) |
LSD1 inhibitor
| Chemical Name: | 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride |
| Purity: | ≥97% (HPLC) |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥99% (HPLC) |
Potent and selective LSD1 inhibitor
| Chemical Name: | rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent LSD1 inhibitor
| Chemical Name: | 4'-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol |
| Purity: | ≥98% (HPLC) |
LSD1 inhibitor
| Chemical Name: | (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Inactive isomer of GSK J1 (Cat. No. 4593)
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% (HPLC) |
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride |
| Purity: | ≥98% (HPLC) |
