Sarafotoxin S6a

Name: Sarafotoxin S6a
Brand: Tocris Bioscience
SKU: 1899

Tocris Bioscience, part of Bio-Techne | Catalog # 1899

COA / SDS

Endothelin receptor agonist

Discontinued Product

1899 has been discontinued. View all Non-selective Endothelin Receptor Agonists products.

Key Product Details

Description:	Endothelin receptor agonist
Molecular Weight:	2514.85

View Full Technical Details for Sarafotoxin S6a

Technical Data
Citations

Biological Activity for Sarafotoxin S6a

Endothelin receptor agonist (EC₅₀ values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

Technical Data for Sarafotoxin S6a

M. Wt	2514.85
Formula	C₁₀₅H₁₅₆N₂₈O₃₄S₅
Single Letter Sequence	CSCKDMTDKECLNFCHQDVIW (Modifications: Disulfide bridge between 1 - 15, 3 - 11)
Storage	Desiccate at -20°C
CAS Number	126738-34-9
PubChem ID	71308664
InChi Key	BOQKWORWRAYXSI-SQCNKGOOSA-N
Smiles	[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Sarafotoxin S6a

References are publications that support the biological activity of the product.

Raffa Endothelin-induced nociception in mice: mediation by ET_A and ET_B receptors. J.Pharmacol.Exp.Ther. 1996 PMID: 8632332
Schoeffter and Randriantsoa Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur.J.Pharmacol. 1993 PMID: 8287901
Minkes Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds. Am.J.Physiol. 1992 PMID: 1348398

Sarafotoxin S6a

Tocris Bioscience, part of Bio-Techne | Catalog # 1899

Key Product Details

Biological Activity for Sarafotoxin S6a

Technical Data for Sarafotoxin S6a

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Sarafotoxin S6a

Product Documents for Sarafotoxin S6a

COA

Certificate of Analysis

SDS

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