Non-selective Endothelin Receptor Agonists: Small Molecules and Peptides
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
3 results for "Non-selective Endothelin Receptor Agonists Small Molecules and Peptides" in Products
3 results for "Non-selective Endothelin Receptor Agonists Small Molecules and Peptides" in Products
Non-selective Endothelin Receptor Agonists: Small Molecules and Peptides
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
Potent vasoconstrictor peptide
| Alternate Names: | ET-1 |
| Purity: | ≥95% (HPLC) |
Potent vasoconstrictor
| Alternate Names: | ET-3 |
| Purity: | ≥95% (HPLC) |
ETA/ETB agonist
| Alternate Names: | ET-2 |
| Purity: | ≥95% (HPLC) |
