SR 140333

Biological Activity for SR 140333

Technical Data for SR 140333

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SR 140333

References for SR 140333

References are publications that support the biological activity of the product.

• Oury-Donat et al. SR 140333, a novel, selective, and potent nonpeptide antagonist of the NK1 tachykinin receptor: characterization on the U373MG cell line. J.Neurochem., 1994;62:1399 PMID: 7510780
• Emonds-Alt et al. In vitro and in vivo biological activities of SR140333, a novel non-peptide tachykinin NK₁ receptor antagonist. Eur.J.Pharmacol., 1993;250:403 PMID: 7509286
• Hall and Brain Inhibition by SR140333 of NK₁ tachykinin receptor-evoked, nitric oxide-dependent vasodilation in the hamster cheek pouch microvasculature in vivo. Br.J.Pharmacol., 1994;113:522 PMID: 7530573
• Nieuwmeyer et al. Ava[L-Pro9,N-MeLeu10] substance P(7-11) (GR 73632) and Sar9, Met(O2)11 increase distention-induced peristalsis through activation of neurokinin-1 receptors on smooth muscle and interstitial cells of Caj J.Pharmacol.Exp.Ther., 2006;317:439 PMID: 16330493