Thalidomide 4'-oxyacetamide-alkylC6-amine

Name: Thalidomide 4'-oxyacetamide-alkylC6-amine
Brand: Tocris Bioscience
SKU: 6968

Tocris Bioscience, part of Bio-Techne | Catalog # 6968

COA / SDS

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Key Product Details

Description:	Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names:	Thalidomide - linker 15
Chemical Name:	N-(6-Aminohexyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	466.92

View Full Technical Details for Thalidomide 4'-oxyacetamide-alkylC6-amine

Technical Data
Citations

Biological Activity for Thalidomide 4'-oxyacetamide-alkylC6-amine

Thalidomide 4'-oxyacetamide-alkylC6-amine is a functionalized cereblon ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkyl linker with amine terminal ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 15

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Thalidomide 4'-oxyacetamide-alkylC6-amine

M. Wt	466.92
Formula	C₂₁H₂₆N₄O₆.HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2376990-31-5
Smiles	NCCCCCCNC(COC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Product Documents for Thalidomide 4'-oxyacetamide-alkylC6-amine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.