Degrader Building Blocks: Small Molecules and Peptides
156 results for "Degrader Building Blocks Small Molecules and Peptides" in Products
156 results for "Degrader Building Blocks Small Molecules and Peptides" in Products
Degrader Building Blocks: Small Molecules and Peptides
UBE2D degrader building block
Chemical Name: | N-[[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-5-isoxazolyl]methyl]-2-propenamide |
Purity: | ≥95% (HPLC) |
Functionalized VHL building block for copper-free click chemistry
Chemical Name: | ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl ((S)-14-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-15,15-dimethyl-12-oxo-3,6,9-trioxa-13-azahexadecyl)carbamate |
Purity: | ≥90% (HPLC) |
Negative control for VH 032, amine (Cat. No. 6462)
Alternate Names: | (S,S,S)-AHPC |
Chemical Name: | (2S,4S)-1-[(2S)-2-Amino-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide dihydrochloride |
Purity: | ≥98% (HPLC) |
Cereblon ligand with terminal piperidine for onward chemistry
Chemical Name: | 3-[1,3-Dihydro-1-oxo-5-[4-(4-piperidinylmethyl)-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione dihydrochloride |
Purity: | ≥94% (HPLC) |
Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
Chemical Name: | 36-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-21,21-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid |
Purity: | ≥90% (HPLC) |
Biotinylated ASGPR ligand for LYTAC research and development
Purity: | ≥90% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
Alternate Names: | (S,R,S)-AHPC-C2-COOH |
Chemical Name: | 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name: | 4-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]butanoic acid |
Purity: | ≥95% (HPLC) |
Functionalized cereblon ligand for PROTAC development
Chemical Name: | 2-(4-(2,6-Dioxopiperidin-3-yl)phenoxy)acetic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal amine for onward chemistry
Chemical Name: | 4-[[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥95% (HPLC) |
Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry
Purity: | ≥90% (HPLC) |
VHL ligand with PEG linker and terminal amine for onward chemistry
Alternate Names: | (S,R,S)-AHPC-PEG4-NH2 |
Chemical Name: | (2S,4R)-1-((S)-17-Amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Alternate Names: | Pomalidomide - linker 4 |
Chemical Name: | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥95% (HPLC) |
Functionalized VHL ligand for PROTACs
Chemical Name: | (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride |
Purity: | ≥98% (HPLC) |
Functionalized photoswitchable cereblon ligand for Degraders
Chemical Name: | (E)-2-(4-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)diazenyl)-2,6-dimethoxyphenoxy)acetic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name: | 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexanoic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name: | 3-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]propanoic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Chemical Name: | 7-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]heptanoic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Chemical Name: | 5-[(8-Aminooctyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal amine for onward chemistry
Alternate Names: | Thalidomide - linker 11 |
Chemical Name: | 4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternate Names: | (S,R,S)-AHPC-C2-NH2 |
Chemical Name: | (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal amine for onward chemistry
Alternate Names: | (S,R,S)-AHPC-PEG2-NH2 |
Chemical Name: | (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
Purity: | ≥95% (HPLC) |
Functionalized cereblon ligand for PROTAC development
Chemical Name: | 2-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenoxy]acetic acid |
Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
Alternate Names: | (S,R,S)-AHPC-amido-C7-acid |
Chemical Name: | 9-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-9-oxononanoic acid |
Purity: | ≥95% (HPLC) |
Cereblon ligand with PEG linker and terminal amine for onward chemistry
Chemical Name: | 4-[(17-Amino-3,6,9,12,15-pentaoxaheptadec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥95% (HPLC) |