Tyrosine Phosphatase Substrate I, DADEY(PO3)LIPQQG
R&D Systems, part of Bio-Techne | Catalog # ES006
Substrate for PTP1B, TC-PTP, SHP-2, and Tyrosine Phosphatase
Key Product Details
Conjugate
Unconjugated
Product Specifications
Source
Asp-Ala-Asp-Glu-Tyr(PO3)-Leu-Ile-Pro-Gln-Gln-Gly
Synthetic phosphopeptide corresponding to amino acids 988 - 998 of the mature EGF receptor (EGF R, Accession # AF288738).
Derived from an autophosphorylation site at Y992 of EGF R.
Purity
>95%, by HPLC.
Predicted Molecular Mass
1328.32 Da
Formulation, Preparation and Storage
ES006
Formulation | Lyophilized from a stock solution in distilled water. |
Reconstitution |
Dissolves in water. 61.3 μL gives a stock solution of substrate at 10 mM concentration |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Lyophilized samples are stable for up to twelve months from date of receipt at -20° C to -70° C. Upon reconstitution, the substrate can be stored at 2° - 8° C for one month or at -20° to -70° C in a manual defrost freezer for three months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light. |
Background: Phosphatase Peptide Substrates
References
- Zhang, Z.Y. et al. (1993) Proc. Natl. Acad. Sci. USA 90:4446.
- Peters, G.H. et al. (2000) J. Biol. Chem. 275:18201.
- Sarmiento, M. et al. (1998) J. Biol. Chem. 273:26368.
- Sugimoto, S. et al. (1993 J. Biol. Chem. 268:22771.
- Van Veldhoven, P.P. and G.P. Mannaerts (1987) Anal. Biochem. 161:45.
Additional Phosphatase Peptide Substrates Products
Product Documents for Tyrosine Phosphatase Substrate I, DADEY(PO3)LIPQQG
Product Specific Notices for Tyrosine Phosphatase Substrate I, DADEY(PO3)LIPQQG
For research use only
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