VH 032 phenol-alkylC4-amine

Name: VH 032 phenol-alkylC4-amine
Brand: Tocris Bioscience
SKU: 6909

Tocris Bioscience, part of Bio-Techne | Catalog # 6909

Citations (1)

COA / SDS

VHL ligand with alkyl linker and terminal amine for onward chemistry

Key Product Details

Description:	VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names:	(S,R,S)-AHPC-phenol-C4-NH2
Chemical Name:	(2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	632.64

View Full Technical Details for VH 032 phenol-alkylC4-amine

Technical Data
Citations

Biological Activity for VH 032 phenol-alkylC4-amine

VH 032 phenol-alkylC4-amine is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 1

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for VH 032 phenol-alkylC4-amine

M. Wt	632.64
Formula	C₂₈H₄₁N₅O₅S.2HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2376990-26-8
Smiles	CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(C)=O)C(C)(C)C)=O)=O)C(OCCCCN)=C2.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for VH 032 phenol-alkylC4-amine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.