5-HT2A Receptor Agonists: Small Molecules and Peptides
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
2 results for "5-HT2A Receptor Agonists Small Molecules and Peptides" in Products
2 results for "5-HT2A Receptor Agonists Small Molecules and Peptides" in Products
5-HT2A Receptor Agonists: Small Molecules and Peptides
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
High affinity and selective 5-HT2A agonist
| Alternate Names: | 25CN-NBOH |
| Chemical Name: | 4-[2-[[(2-Hydroxyphenyl)methyl]amino]ethyl]-2,5-dimethoxybenzonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity and potent 5-HT2A agonist
| Chemical Name: | (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide |
| Purity: | ≥99% (HPLC) |
