ABLIM1: Proteins and Enzymes

ABLIM1 (actin-binding LIM protein 1) was isolated as a cDNA that encoded dematin-like polypeptides in the human retina. Dematin and dematin-like proteins are actin-associated proteins that play roles in cytoskeletal regulation and morphogenesis. ABLIM1 is a LIM (Lin-11 Isl-1 mec03) motif containing protein characterized by the presences of cysteine-rich double zinc-fingers that play a role in diverse developmental programs.