Activin B: Proteins and Enzymes
Activin B is a TGF-beta superfamily cytokine that regulates cellular migration by inducing actin stress fiber formation. It signals through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. It also modulates signaling through E-Cadherin and Integrin beta 3. Activin B upregulation is associated with tumor cell adhesion, migration, and metastasis.
It also promotes wound healing through increased cellular migration. Activin B additionally induces hair follicle formation and expression of Hepicin in the liver, but it inhibits lipolysis in adipocytes and glucose-stimulated calcium influx in pancreatic beta cells. Alterations of Activin B serum levels of Activin B are associated with ectopic pregnancy and chronic fatigue syndrome, and it is upregulated in alveolar epithelial cells in pulmonary fibrosis.
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2 results for "Activin B Proteins and Enzymes" in Products
2 results for "Activin B Proteins and Enzymes" in Products
Activin B: Proteins and Enzymes
Activin B is a TGF-beta superfamily cytokine that regulates cellular migration by inducing actin stress fiber formation. It signals through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. It also modulates signaling through E-Cadherin and Integrin beta 3. Activin B upregulation is associated with tumor cell adhesion, migration, and metastasis.
It also promotes wound healing through increased cellular migration. Activin B additionally induces hair follicle formation and expression of Hepicin in the liver, but it inhibits lipolysis in adipocytes and glucose-stimulated calcium influx in pancreatic beta cells. Alterations of Activin B serum levels of Activin B are associated with ectopic pregnancy and chronic fatigue syndrome, and it is upregulated in alveolar epithelial cells in pulmonary fibrosis.
Products:
| Source: | CHO |
| Accession #: | P09529.2 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | Q04999 |
| Applications: | BA |
