Adenosine A1 Receptor Agonists: Small Molecules and Peptides
Adenosine A1 Receptor (ADORA1) is an adenosine receptor that belongs to the G protein-coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The ADORA1 receptor inhibits adenylyl cyclase, and plays a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication.
6 results for "Adenosine A1 Receptor Agonists Small Molecules and Peptides" in Products
6 results for "Adenosine A1 Receptor Agonists Small Molecules and Peptides" in Products
Adenosine A1 Receptor Agonists: Small Molecules and Peptides
Adenosine A1 Receptor (ADORA1) is an adenosine receptor that belongs to the G protein-coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The ADORA1 receptor inhibits adenylyl cyclase, and plays a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication.
Highly selective A1 agonist
| Chemical Name: | N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine |
| Purity: | ≥98% (HPLC) |
Highly selective and potent A1 receptor agonist
| Chemical Name: | 2-Chloro-N-cyclopentyl-2'-methyladenosine |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
| Chemical Name: | [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone |
| Purity: | ≥98% (HPLC) |
Potent and selective A1 agonist
| Chemical Name: | N-Cyclohexyl-2'-O-methyladenosine |
| Purity: | ≥99% (HPLC) |
Potent and selective A1 agonist
| Alternate Names: | CPA |
| Chemical Name: | N-Cyclopentyladenosine |
| Purity: | ≥99% (HPLC) |
Potent and selective A1 agonist
| Alternate Names: | CCPA |
| Chemical Name: | 2-Chloro-N-cyclopentyladenosine |
| Purity: | ≥98% (HPLC) |
