alpha-L-Iduronidase/IDUA Products
alpha-L-Iduronidase, encoded by the IDUA gene, is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non-reducing terminal a-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue, and organ damage.
20 results for "alpha-L-Iduronidase/IDUA" in Products
20 results for "alpha-L-Iduronidase/IDUA" in Products
alpha-L-Iduronidase/IDUA Products
alpha-L-Iduronidase, encoded by the IDUA gene, is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non-reducing terminal a-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue, and organ damage.
NS0-expressed
Source: | NS0 |
Accession #: | AAA81589 |
Applications: | EnzAct |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, IP, ICC |
His-tag Avi-tag
Source: | CHO |
Accession #: | P35475.2 |
Applications: | BA, EnzAct |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #452619 |
Applications: | WB |
CHO-expressed (aa 26-653)
Source: | CHO |
Accession #: | P35475.2 |
Applications: | EnzAct |
CHO-expressed (aa 28-653 H33Q)
Source: | CHO |
Accession #: | P35475.2 |
Applications: | EnzAct |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB |
Source: | NS0 |
Accession #: | P48441 |
Applications: | EnzAct |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Mouse |
Details: | Rabbit Polyclonal |
Applications: | WB |
Applications: | AC |
Reactivity: | Human |
Details: | Rabbit Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Applications: | ELISA |
Applications: | ELISA |
Applications: | AC |
Selective Mps1 kinase inhibitor
Chemical Name: | 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride |
Purity: | ≥98% |