APC: Small Molecules and Peptides
APC is a ubiquitous, tumor-suppressor protein. APC mutations are common in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains, including an EB1, DLG (PDZ sequence) and PSD-93 domain that bind to cytoskeletal elements. In addition to beta-catenin degradation, APC is involved in cell cycle, division and migration.
2 results for "APC Small Molecules and Peptides" in Products
2 results for "APC Small Molecules and Peptides" in Products
APC: Small Molecules and Peptides
APC is a ubiquitous, tumor-suppressor protein. APC mutations are common in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains, including an EB1, DLG (PDZ sequence) and PSD-93 domain that bind to cytoskeletal elements. In addition to beta-catenin degradation, APC is involved in cell cycle, division and migration.
Cell-permeable APC/C inhibitor
| Chemical Name: | Methyl (2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoate |
| Purity: | ≥90% (HPLC) |
Wnt pathway inhibitor
| Chemical Name: | 4-[4-(4-Methoxyphenyl)-5-[[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thio]-4H-1,2,4-triazol-3-yl]-pyridine |
| Purity: | ≥99% (HPLC) |
