Axin-1: Proteins and Enzymes
Axin-1 is a negative regulator of the Wnt signaling pathway, which is involved in regulation of embryonic axis formation in vertebrates. Axin-1 binds to beta-catenin and glycogen synthase kinase-3 (GSK-3) to promote beta-catenin phosphorylation and subsequent degradation. Axin-1 also binds to the adenomatous polyposis coli (APC) gene, a known tumor suppressor that also regulates beta-catenin.
2 results for "Axin-1 Proteins and Enzymes" in Products
2 results for "Axin-1 Proteins and Enzymes" in Products
Axin-1: Proteins and Enzymes
Axin-1 is a negative regulator of the Wnt signaling pathway, which is involved in regulation of embryonic axis formation in vertebrates. Axin-1 binds to beta-catenin and glycogen synthase kinase-3 (GSK-3) to promote beta-catenin phosphorylation and subsequent degradation. Axin-1 also binds to the adenomatous polyposis coli (APC) gene, a known tumor suppressor that also regulates beta-catenin.
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |