B7-H4 Products
B7-H4, also known as B7x and B7S1, is an immune costimulatory protein that is expressed on the surface of activated lymphocytes, macrophages, monocytes, dendritic cells, epithelial cells, and bone marrow-derived mesenchymal stem cells. Its binding to activated T cells dampens T cell responses and induces cell cycle arrest in the T cell. Reverse signaling can induce either cell cycle arrest or apoptosis in the B7-H4 expressing cell. B7-H4 is upregulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 functions as a decoy molecule and is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients.
367 results for "B7-H4" in Products
367 results for "B7-H4" in Products
B7-H4 Products
B7-H4, also known as B7x and B7S1, is an immune costimulatory protein that is expressed on the surface of activated lymphocytes, macrophages, monocytes, dendritic cells, epithelial cells, and bone marrow-derived mesenchymal stem cells. Its binding to activated T cells dampens T cell responses and induces cell cycle arrest in the T cell. Reverse signaling can induce either cell cycle arrest or apoptosis in the B7-H4 expressing cell. B7-H4 is upregulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 functions as a decoy molecule and is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #973816 |
| Applications: | Flow, IHC, CyTOF-ready |
| Source: | NS0 |
| Accession #: | NP_078902 |
| Applications: | BA |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2582H |
| Applications: | WB, Simple Western, Flow, CyTOF-ready, ICC |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
| Source: | HEK293 |
| Accession #: | Q7Z7D3 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | NP_078902 |
| Applications: | BA |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2318A |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2319B |
| Applications: | WB, Flow, IHC, CyTOF-ready |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2318A |
| Applications: | WB, Flow, IHC, CyTOF-ready |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #973816R |
| Applications: | Flow, IHC, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2582H |
| Applications: | Flow |
Biotinylated
| Source: | HEK293 |
| Accession #: | Q7Z7D3 |
| Applications: | BA, BA |
| Source: | NS0 |
| Accession #: | Q7TSP5 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #973816R |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #973815 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #973808 |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #297219 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2582H |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2585H |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2582H |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2582H |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | AAP37284 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #297219 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #935317 |
| Applications: | Flow |
