BNIP3: Lysates
BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.
1 result for "BNIP3 Lysates" in Products
1 result for "BNIP3 Lysates" in Products
BNIP3: Lysates
BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.
| Applications: | WB |
![Western Blot: BNIP3 Overexpression Lysate [NBL1-08014]](https://resources.bio-techne.com/images/products/BNIP3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-08014-img0002.jpg "Western Blot: BNIP3 Overexpression Lysate [NBL1-08014]")