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BNIP3 Products

BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.

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1 result for "BNIP3" in Products

1 result for "BNIP3" in Products

BNIP3 Products

BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.

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Applications: IHC, WB
Reactivity: Human, Rat, Porcine, Chicken, Mouse (Negative), +1 More
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