Cannabinoid R2/CB2 Agonists: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
4 results for "Cannabinoid R2/CB2 Agonists Small Molecules and Peptides" in Products
4 results for "Cannabinoid R2/CB2 Agonists Small Molecules and Peptides" in Products
Cannabinoid R2/CB2 Agonists: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
Potent and selective CB2 agonist
| Chemical Name: | (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
| Purity: | ≥98% (HPLC) |
Potent and selective CB2 agonist
| Chemical Name: | (1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol |
| Purity: | ≥98% (HPLC) |
Potent and selective CB2 partial agonist; orally biovailable
| Chemical Name: | 3-Cyclopropyl-1-[[4-[6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl]phenyl]methyl]-2,4-imidazolidinedione hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity, selective CB2 agonist
| Chemical Name: | N-Cyclohexyl-7-chloro-1-[2-(4-morpholinyl)ethyl]quinolin-4(1H)-one-3-carboxamide |
| Purity: | ≥99% (HPLC) |
