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Caspase-1: Small Molecules and Peptides

Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa and two 10 kDa subunits which associate following cleavage of inactive precursors. Caspase...

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3 results for "Caspase-1 Small Molecules and Peptides" in Products

3 results for "Caspase-1 Small Molecules and Peptides" in Products

Caspase-1: Small Molecules and Peptides

Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa and two 10 kDa subunits which associate following cleavage of inactive precursors. Caspase...

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High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

Potent and selective inhibitor of caspases 1, 5 and 4

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