Caspase-10: Proteins and Enzymes
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
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2 results for "Caspase-10 Proteins and Enzymes" in Products
2 results for "Caspase-10 Proteins and Enzymes" in Products
Caspase-10: Proteins and Enzymes
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
Products:
| Source: | E. coli |
| Accession #: | AAC50644 |
| Applications: | EnzAct |
| Applications: | AC |