Caspase-10: Small Molecules and Peptides
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
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2 results for "Caspase-10 Small Molecules and Peptides" in Products
2 results for "Caspase-10 Small Molecules and Peptides" in Products
Caspase-10: Small Molecules and Peptides
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
Products:
Promotes assembly and inhibits disassembly of microtubules
| Alternate Names: | Paclitaxel |
| Chemical Name: | [2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester benzenepropanoic acid |
| Purity: | ≥98% (HPLC) |
