CD59: Lysates

CD59 is a GPI-anchored membrane glycoprotein that functions to inhibit formation of the complement membrane attack complex and thereby prevent cell injury. CD59 is expressed on erythrocytes and on all peripheral blood leukocytes. In mouse, the gene encoding CD59 has been duplicated, giving rise to CD59a and CD59b. The two proteins are differentially expressed in tissues and share approximately 65% amino acid sequence identity.