CD8: Proteins and Enzymes
CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.
9 results for "CD8 Proteins and Enzymes" in Products
9 results for "CD8 Proteins and Enzymes" in Products
CD8: Proteins and Enzymes
CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.
Analyzed by SEC-MALS.
| Source: | HEK293 |
| Accession #: | P01732 (CD8 alpha ) & P10966 (CD8 beta) |
| Applications: | BA |
Analyzed by SEC-MALS.
| Source: | HEK293 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P01731 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | P01732.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P41688 |
| Source: | CHO |
| Accession #: | P01732.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | AAL55392 |
| Applications: | AC |
| Applications: | AC |