CTLA-4: ELISA Kits
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
3 results for "CTLA-4 ELISA Kits" in Products
3 results for "CTLA-4 ELISA Kits" in Products
CTLA-4: ELISA Kits
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Applications: | ELISA |
![ELISA: Human CTLA-4 ELISA Kit (Colorimetric) [NBP1-91268]](https://resources.bio-techne.com/images/products/CTLA-4-ELISA-Kit-ELISA-NBP1-91268-img0001.jpg "ELISA: Human CTLA-4 ELISA Kit (Colorimetric) [NBP1-91268]")
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA |
