CXCR2/IL-8RB: Lysates
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
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CXCR2/IL-8RB: Lysates
CXCR2/IL-8RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8RB is expressed on neutrophils and activates neutrophil chemotaxis.
Similar to the closely related CXCR1/IL-8RA, CXCR2/IL-8RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.
Products:
| Applications: | WB |
![Western Blot: CXCR2/IL-8RB Overexpression Lysate [NBL1-11969]](https://resources.bio-techne.com/images/products/CXCR2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11969-img0002.jpg "Western Blot: CXCR2/IL-8RB Overexpression Lysate [NBL1-11969]")