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Cyr61/CCN1: Simple Plex

Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.

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3 results for "Cyr61/CCN1 Simple Plex" in Products

3 results for "Cyr61/CCN1 Simple Plex" in Products

Cyr61/CCN1: Simple Plex

Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.

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Applications: Simple Plex

Simple Plex Human Cyr61/CCN1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Human Cyr61/CCN1 Simple Plex Cartridge Kit

Applications: Simple Plex
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