Deubiquitinating Enzyme Inhibitors: Small Molecules and Peptides
Deubiquitinating enzymes (also known as DUBs) are a group of proteases. They help catalyze the cleavage of protein-ubiquitin bonds. By removing these modifications, DUBs counteract the activity of ubiquitin ligases, which add ubiquitin molecules to target proteins.
7 results for "Deubiquitinating Enzyme Inhibitors Small Molecules and Peptides" in Products
7 results for "Deubiquitinating Enzyme Inhibitors Small Molecules and Peptides" in Products
Deubiquitinating Enzyme Inhibitors: Small Molecules and Peptides
Deubiquitinating enzymes (also known as DUBs) are a group of proteases. They help catalyze the cleavage of protein-ubiquitin bonds. By removing these modifications, DUBs counteract the activity of ubiquitin ligases, which add ubiquitin molecules to target proteins.
Broad spectrum DUB inhibitor
| Chemical Name: | 2,6-Diamino-3,5-dithiocyanopyridine |
| Purity: | ≥98% (HPLC) |
Selective USP7 inhibitor
| Chemical Name: | 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
| Purity: | ≥98% (HPLC) |
USP10 and USP13 inhibitor; inhibits autophagy
| Chemical Name: | 6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Potent and selective USP1-UAF1 allosteric inhibitor
| Chemical Name: | 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
USP7 inhibitor
| Chemical Name: | 1-[5-[(2,4-Difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Purity: | ≥99% (HPLC) |
Selective USP30 inhibitor
| Chemical Name: | N-(1-((5-(N-(tert-Butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective inhibitor of USP21; also NF-κB activator
| Chemical Name: | N-[(1R)-1-[[[5-[(4-Cyanophenyl)methyl]-1,3,4-thiadiazol-2-yl]amino]carbonyl]-3-methylbutyl]-1-(trifluoromethyl)cyclohexanecarboxamide |
| Purity: | ≥98% (HPLC) |
