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Dkk-2 Products

Dickkopf related protein 2 (Dkk-2) is a member of the Dickkopf family of secreted Wnt modulators. Dkk proteins modify Wnt engagement of a receptor complex composed of a Frizzled protein and either LRP-5 or LRP-6. Kremen-1 and Kremen-2 are also high affinity receptors for Dkk-1 and Dkk-2. Depending on the cellular context, Dkk-2 can either activate or inhibit canonical Wnt signaling. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformation. Dkk-2 expression is induced by Wnts in bone and is thought to enhance bone density by promoting terminal differentiation of osteoblasts and mineral deposition.

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53 results for "Dkk-2" in Products

53 results for "Dkk-2" in Products

Dkk-2 Products

Dickkopf related protein 2 (Dkk-2) is a member of the Dickkopf family of secreted Wnt modulators. Dkk proteins modify Wnt engagement of a receptor complex composed of a Frizzled protein and either LRP-5 or LRP-6. Kremen-1 and Kremen-2 are also high affinity receptors for Dkk-1 and Dkk-2. Depending on the cellular context, Dkk-2 can either activate or inhibit canonical Wnt signaling. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformation. Dkk-2 expression is induced by Wnts in bone and is thought to enhance bone density by promoting terminal differentiation of osteoblasts and mineral deposition.

Products:

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Applications: WB, IHC
Reactivity: Mouse
Applications: IHC, ICC, ICFlow
Reactivity: Human
Applications: IHC, ICC/IF
Reactivity: Human, Mouse
Applications: WB
Reactivity: Mouse
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: ELISA
Applications: ELISA
Applications: WB
Applications: ELISA
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: AC
Applications: IHC, ICC/IF, Flow
Reactivity: Human
Applications: IHC, ICC/IF, Flow
Reactivity: Human
Applications: IHC, ICC/IF, Flow
Reactivity: Human
Applications: IHC, ICC/IF, Flow
Reactivity: Human
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