E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
303 results for "E-Cadherin" in Products
303 results for "E-Cadherin" in Products
E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, CyTOF-ready, +2 More |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, CyTOF-ready, +2 More |
| Reactivity: | Human, Mouse, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #7H12 |
| Applications: | IHC, WB, ICC/IF, ELISA, Flow, +1 More |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #180215 |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #180224 |
| Applications: | WB, Flow, IHC, CyTOF-ready, ICC |
