E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
2 results for "E-Cadherin" in Products
2 results for "E-Cadherin" in Products
E-Cadherin Products
E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.
| Reactivity: | Human, Mouse, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #7H12 |
| Applications: | IHC, WB, ICC/IF, ELISA, Flow, +1 More |
| Reactivity: | Human, Mouse, Canine, Bovine, Feline |
| Details: | Rat IgG1 Monoclonal Clone #DECMA-1 |
| Applications: | IHC, WB, ICC/IF, IP, MA |
![Western Blot: E-Cadherin Antibody (DECMA-1) [NB120-11512]](https://resources.bio-techne.com/images/products/E-Cadherin-Antibody-DECMA-1-Western-Blot-NB120-11512-img0006.jpg "Western Blot: E-Cadherin Antibody (DECMA-1) [NB120-11512]")