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E-Selectin/CD62E: Simple Plex

E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.

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3 results for "E-Selectin/CD62E Simple Plex" in Products

3 results for "E-Selectin/CD62E Simple Plex" in Products

E-Selectin/CD62E: Simple Plex

E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.

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Applications: Simple Plex

Simple Plex Human E-Selectin/CD62E assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Human E-Selectin/CD62E Simple Plex Cartridge Kit

Applications: Simple Plex
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