FGF basic/FGF2/bFGF Products
FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.
227 results for "FGF basic/FGF2/bFGF" in Products
227 results for "FGF basic/FGF2/bFGF" in Products
FGF basic/FGF2/bFGF Products
FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.
| Sensitivity: | 3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 10 - 640 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | NP_001997 |
| Applications: | BA, BA |
Intended for preclinical researchers who may transition to GMP FGF basic/FGF2 for their clinical work
| Source: | E. coli |
| Accession #: | NP_001997.5 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001997 |
| Applications: | BA |
| Sensitivity: | 0.07 pg/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 pg/mL (Serum, EDTA Plasma, Citrate Plasma, Urine) |
| Source: | E. coli |
| Accession #: | P15655 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #8W6M5 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: FGF basic/FGF2/bFGF Antibody (8W6M5) [NBP3-15367]](https://resources.bio-techne.com/images/products/FGF-basic-FGF2-bFGF-Antibody-8W6M5-Western-Blot-NBP3-15367-img0006.jpg "Western Blot: FGF basic/FGF2/bFGF Antibody (8W6M5) [NBP3-15367]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Sensitivity: | 3.68 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma) |
| Source: | E. coli |
| Accession #: | P13109 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | NP_001997.5 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001997.5 |
| Applications: | BA |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P03969 |
| Applications: | BA |
| Source: | Bovine Brain |
| Applications: | BA |
| Reactivity: | Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #10060 |
| Source: | E. coli |
| Accession #: | P03969 |
| Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI3D9 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: FGF basic/FGF2/bFGF Antibody (OTI3D9) [NBP1-47749]](https://resources.bio-techne.com/images/products/FGF-basic-FGF2-Antibody-3D9-Western-Blot-NBP1-47749-img0008.jpg "Western Blot: FGF basic/FGF2/bFGF Antibody (OTI3D9) [NBP1-47749]")
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.