FRS2: Proteins and Enzymes
FRS2 (FGF R substrate 2; also known as SNT and FRS2 alpha) is a 70-90 kDa member of the FRS family of lipid-anchored docking proteins. It is an intermediary between FGF R and other RTK receptors and their Ras/MAPK signaling cascades. FRS2 contains a membrane-anchoring myristoylation signal (aa 1-6), a PTB domain (aa 13-115) that interacts with FGF and NGF receptors, and a C-terminal Tyr-rich region (aa 196-471) that serves as a docking site for GRB-2 and SHP-2.
2 results for "FRS2 Proteins and Enzymes" in Products
2 results for "FRS2 Proteins and Enzymes" in Products
FRS2: Proteins and Enzymes
FRS2 (FGF R substrate 2; also known as SNT and FRS2 alpha) is a 70-90 kDa member of the FRS family of lipid-anchored docking proteins. It is an intermediary between FGF R and other RTK receptors and their Ras/MAPK signaling cascades. FRS2 contains a membrane-anchoring myristoylation signal (aa 1-6), a PTB domain (aa 13-115) that interacts with FGF and NGF receptors, and a C-terminal Tyr-rich region (aa 196-471) that serves as a docking site for GRB-2 and SHP-2.
| Applications: | WB, ELISA, IP, MA, AP, +1 More |
| Applications: | WB, ELISA, MA, AP |
