gamma-Secretase Modulators: Small Molecules and Peptides
Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques. Cleavage of APP by the beta- and gamma-secretases generates the Ab...
2 results for "gamma-Secretase Modulators Small Molecules and Peptides" in Products
2 results for "gamma-Secretase Modulators Small Molecules and Peptides" in Products
gamma-Secretase Modulators: Small Molecules and Peptides
Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques. Cleavage of APP by the beta- and gamma-secretases generates the Ab...
γ-secretase modulator; Notch-sparing
| Chemical Name: | (3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone |
| Purity: | ≥98% (HPLC) |
γ-secretase pseudo-inhibitor
| Chemical Name: | (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide |
| Purity: | ≥98% (HPLC) |
