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GDF-3 Products

GDF-3 (Growth Differentiation Factor-3; Vgr-2) is a TGF-beta superfamily member that is expressed in undifferentiated embryonic stem (ES) cells, white adipose tissue, and the brain. GDF-3 is upregulated in adipocytes by a high-fat diet, promoting adipogenesis and obesity.

Both proGDF-3 and mature GDF-3 lacking the propeptide can oppose BMP activity. Inhibition of BMP-2 signaling by GDF-3 supports the pluripotency of ES cells. During embryogenesis, GDF-3 cooperates with GDF-1, plays a role in anterior visceral endoderm development. GDF-3 signals through the receptors Activin RIB/ALK-4 and ALK-7.

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150 results for "GDF-3" in Products

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150 results for "GDF-3" in Products

GDF-3 Products

GDF-3 (Growth Differentiation Factor-3; Vgr-2) is a TGF-beta superfamily member that is expressed in undifferentiated embryonic stem (ES) cells, white adipose tissue, and the brain. GDF-3 is upregulated in adipocytes by a high-fat diet, promoting adipogenesis and obesity.

Both proGDF-3 and mature GDF-3 lacking the propeptide can oppose BMP activity. Inhibition of BMP-2 signaling by GDF-3 supports the pluripotency of ES cells. During embryogenesis, GDF-3 cooperates with GDF-1, plays a role in anterior visceral endoderm development. GDF-3 signals through the receptors Activin RIB/ALK-4 and ALK-7.

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Applications: WB, IHC, ICC
Reactivity: Human, Mouse
Applications: WB
Reactivity: Mouse
Applications: Neut
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: ICC
Reactivity: Human
Applications: IHC, ICC/IF
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Applications: ELISA
Applications: IHC, WB
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB
Applications: ELISA
Applications: IHC
Reactivity: Human
Applications: IHC
Reactivity: Mouse
Applications: WB
Reactivity: Human, Rat, Porcine
Applications: Bind
Applications: IHC, ICC/IF
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human
Applications: AC
Applications: IHC, ICC/IF
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ICC/IF
Reactivity: Human

Recombinant Monoclonal Antibody

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