GINS4: Proteins and Enzymes

The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), andPsf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication inyeast and Xenopus egg extracts (Ueno et al., 2005 (PubMed 16287864)). See GINS1 for additional information about theGINS complex.(supplied by OMIM)