Glucagon R/GCGR: Small Molecules and Peptides
Glucagon R (GCGR) is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of GCGR is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in GCGR are a cause of non-insulin-dependent diabetes mellitus.
4 results for "Glucagon R/GCGR Small Molecules and Peptides" in Products
4 results for "Glucagon R/GCGR Small Molecules and Peptides" in Products
Glucagon R/GCGR: Small Molecules and Peptides
Glucagon R (GCGR) is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of GCGR is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in GCGR are a cause of non-insulin-dependent diabetes mellitus.
Endogenous glucagon receptor agonist
| Purity: | ≥95% (HPLC) |
Glucagon receptor antagonist
| Purity: | ≥95% (HPLC) |
Negative allosteric modulator of glucagon and GLP-1 receptors
| Chemical Name: | 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide |
| Purity: | ≥98% (HPLC) |
Potent, orally active human glucagon receptor antagonist
| Chemical Name: | 4-[3-(5-Bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine |
| Purity: | ≥99% (HPLC) |
